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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
25.45
Human Site:
T251
Identified Species:
40
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
T251
P
D
G
D
H
N
I
T
E
L
P
Q
A
V
A
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
T251
P
D
G
D
H
N
I
T
E
L
P
Q
A
V
A
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
T251
P
D
G
D
H
N
I
T
E
L
P
Q
A
V
A
Dog
Lupus familis
XP_533920
792
88144
T251
P
D
G
E
H
N
I
T
E
L
P
Q
A
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
T251
P
D
G
E
H
N
T
T
E
L
P
Q
A
V
A
Rat
Rattus norvegicus
NP_001011980
470
52521
T251
P
D
G
E
H
N
T
T
E
L
P
Q
A
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
M251
Q
D
G
D
H
N
V
M
E
L
P
Q
V
Y
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
T250
Q
D
E
E
H
N
I
T
E
L
P
Q
V
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
V250
D
D
E
Q
S
H
V
V
L
A
Q
T
L
K
S
Honey Bee
Apis mellifera
XP_395421
413
48031
K244
G
L
S
K
G
V
K
K
L
V
Q
A
K
I
P
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
D279
S
D
S
E
F
E
G
D
Q
Q
E
V
E
L
P
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
L134
S
M
Y
A
S
Q
F
L
H
H
P
L
L
I
L
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
N131
C
P
Q
D
L
F
K
N
A
P
L
I
V
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
L179
I
D
I
N
T
V
K
L
S
T
C
Q
R
L
V
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
I260
A
Y
T
S
E
S
E
I
E
D
D
A
I
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
60
N.A.
N.A.
60
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
N.A.
N.A.
73.3
N.A.
26.6
13.3
26.6
13.3
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
7
7
0
14
40
0
40
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
74
0
34
0
0
0
7
0
7
7
0
0
0
0
% D
% Glu:
0
0
14
34
7
7
7
0
60
0
7
0
7
0
0
% E
% Phe:
0
0
0
0
7
7
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
47
0
7
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
54
7
0
0
7
7
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
34
7
0
0
0
7
7
14
0
% I
% Lys:
0
0
0
7
0
0
20
7
0
0
0
0
7
7
0
% K
% Leu:
0
7
0
0
7
0
0
14
14
54
7
7
14
20
7
% L
% Met:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
54
0
7
0
0
0
0
0
0
0
% N
% Pro:
40
7
0
0
0
0
0
0
0
7
60
0
0
0
14
% P
% Gln:
14
0
7
7
0
7
0
0
7
7
14
60
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% R
% Ser:
14
0
14
7
14
7
0
0
7
0
0
0
0
0
27
% S
% Thr:
0
0
7
0
7
0
14
47
0
7
0
7
0
0
0
% T
% Val:
0
0
0
0
0
14
14
7
0
7
0
7
20
47
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
0
0
0
0
0
0
0
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _